|Chemical Names:||Testosterone; 58-22-0; Testosteron; Androderm; Mertestate; Sustanon More…|
|Molecular Weight:||288.431 g/mol|
|Drug Information:||Drug Indication Therapeutic Uses Clinical Trials FDA Orange Book FDA UNII|
|Safety Summary:||Laboratory Chemical Safety Summary (LCSS)|
Testosterone is a potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Testosterone is an Androgen. The mechanism of action of testosterone is as an Androgen Receptor Agonist. The chemical classification of testosterone is Androstanes.
Therapeutic Testosterone is a synthetic form of the endogenous androgenic steroid testosterone. In vivo, testosterone is irreversibly converted to dihydrotestosterone (DHT) in target tissues by the enzyme 5-alpha reductase. Testosterone or DHT ligand-androgen receptor complexes act as transcription factor complexes, stimulating the expression of various responsive genes. DHT binds with higher affinity to androgen receptors than testosterone, activating gene expression more efficiently. In addition, testosterone is irreversibly converted to estradiol by the enzyme complex aromatase, particularly in the liver and adipose tissue. Testosterone and DHT promote the development and maintenance of male sex characteristics related to the internal and external genitalia, skeletal muscle, and hair follicles; estradiol promotes epiphyseal maturation and bone mineralization. Due to rapid metabolism by the liver, therapeutic testosterone is generally administered as an ester derivative.
SustaTREX 250® – Testosterone Mix 350mg / 1ml, 10ml vials