|Chemical Names:||Liothyronine; Triiodothyronine; 3,3′,5-Triiodo-L-thyronine; 6893-02-3; Liothyronin; Tresitope More…|
|Molecular Weight:||650.977 g/mol|
|Drug Information:||Drug Indication Therapeutic Uses Clinical Trials FDA Orange Book FDA UNII|
|Safety Summary:||Laboratory Chemical Safety Summary (LCSS)|
Liothyronine is a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5′ position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
Liothyronine is a l-Triiodothyronine. The chemical classification of liothyronine is Triiodothyronine.
Liothyronine is a therapeutic formulation of the primary physiologically active form of endogenous thyroid hormone. In vivo, triiodothyronine enters the nucleus and binds to nuclear thyroid hormone receptors that subsequently bind to thyroid response elements (TREs) located in target genes. Receptor binding by triiodothyronine in combination with recruited coactivators results in maximal transcriptional activation after binding to TREs; in general, binding of thyroid hormone receptor alone to TREs leads to repression of gene transcription (NCI04)
ThyroTREX 25® – t3 – Triiodothyronine 25mcg/ 1tab , 100 tabs