MasterTrex®150

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MasterTrex®150 10ml vial

Drostanolone Propionate 150mg/ml, 10 mL Multidose Vial

 

 

Therapeutic Class:
Anabolic Agent

Composition:

Each 1 ml of MasterTREX150 contains

150 mg Drostanolone Propionate

Ethlyl Oleate q.s.

For Intramuscular Administration

Indication & Dosage:

Intramuscular

For use in females, for palliation of androgenresponsive recurrent
mammary cancer in women who are more than one year but less
than five years postmenopausal.

The dose of these medicines will be different for different patients. 

Follow your doctor’s orders or the directions on the label . The following

 information includes only the average doses of these medicines. If your

dose is different, do not change it unless your doctor tells you to do so.

    Contraindications:

Androgen – dependent carcinoma of the prostate or of the male mammary gland.
Hypercalcaemia accompanying malignant tumours Past or present liver tumours.
Hypersensitivity to the active substance or to any of the excipients. 

Special Precautions              
Cardiovascular disorders, skeletal metastases, renal or hepatic impairment,
epilepsy, migraine, diabetes or other conditions which may be aggravated by
fluid retention, eg heart failure. Elderly, prepubertal boys. Monitor signs of
virilization (females) and development of priapism or excessive sexual stimulation
(males). Periodic haemoglobin, lipid determinations and rectal prostate examination.
    Adverse Drug Reactions   
All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most COMMON side effects persist or become

bothersome:Acne; unnatural hair growth; enlarging clitoris; hoarseness or deepening
of voice; irregular menstrual

periods; unnatural hair growth; unusual hair loss;Seek medical attention right away if any of

 these SEVERE side effects occur:Bone pain; nausea or vomiting; sore tongue; swelling of

feet or lower legs; unusual bleeding; unusual weight gain; Black, tarry, or light-colored stools;

dark-colored urine; purple- or red-colored spots on body or inside the mouth or nose; sore

throat and/or fever; vomiting of blood;This is not a complete list of all side effects that may

occur. If you have questions or need medical advice about side effects, contact your doctor

or health care provider.  
   Drug Interactions                
Enhance activities of ciclosporine, antidiabetics, thyroxine, anticoagulants.
Long term use of testosterone may cause resistance to effects of neuromuscular
blockers. Enhance fluid retention from corticosteroids.
    Mechanism of Action         
Dromostanolone is a synthetic androgenic anabolic steroid and is approximately 5 times as
potent as natural methyltestosterone. Like testosterone and other androgenic hormones,
dromostanolone binds to the androgen receptor. This causes downstream genetic
transcriptional changes. This ultimately causes retention of nitrogen, potassium, and
phosphorus; increases protein anabolism; and decreases amino acid catabolism.
The antitumour activity of dromostanolone appears related to reduction or competitive
inhibition of prolactin receptors or estrogen receptors or production.

    Storage:

Store at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly-closed container. Store away from heat, moisture, and light.

Do not store in the bathroom. Keep out of the reach of children and away from pets.

Concentrex Laboratiories N. V., Moerstraat 58, 9031, Gent, Belgium

Reg. No. Licence: 253/55-C9/2010/BE
Manufactured under WHO cGMP guidelines
www.concentrexlabs.com
Date of Preparation : 19 july 2010