PrimoTrex®150

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PrimoTrex®150 10ml vial

Methenolone Enanthate 150mg/ml

 

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Therapeutic Class:
Anabolic Agent

Composition:

Each 1 ml of PRIMOTREX150 contains:

150 mg Methenolone Enanthate

Ethlyl Oleate q.s.

 

For Intramuscular Administration


Indication & Dosage:

Intramuscular

Postmenopausal osteoporosis

Adult: As enantate: 100 mg every 2 wk,

then reduce to once every 3-4 wk after an initial response.

Progressive breast cancer

Adult: As enantate: 100 mg every 1-2 wk

or 200 mg every 2-3 wk.

    Contraindications:

Hypercalcaemia or hypercalciuria, males with breast or prostate carcinoma.
Pregnancy and lactation.
    Special Precautions          
Lactation; CV disorders, renal or hepatic impairment, epilepsy, migraine, DM,

conditions aggravated by fluid retention. Children. Regularly examine prostate in men.

    Adverse Drug Reactions   

Fluid and electrolyte retention, psychiatric effects, hypercalcaemia, impaired glucose

tolerance, increased bone growth and skeletal weight.

Men: Impotence, priapism, azoospermia, prostatic hypertrophy; gynaecomastia, hirsutism,

 male pattern baldness, acne, seborrhoea, oedema, cholestatic jaundice.

Women: Virilisation, amenorrhoea, menstrual irregularities, suppressed lactation,

increased libido.

Children: Premature closure of epiphyses, stops linear growth, virilisation symptoms.                

    Drug Interactions               
May enhance effects of antidiabetics, ciclosporin, levothyroxine, warfarin.

Resistance to the effects of neuromuscular blockers may occur.
Lab Interference

 

May interfere with glucose tolerance and thyroid function tests.                                                                                                                                                                                                 

    Pregnancy Category
Category X: Studies in animals or human beings have demonstrated foetal

abnormalities or there is evidence of foetal risk based on human experience

or both, and the risk of the use of the drug in pregnant women clearly

outweighs any possible benefit. The drug is contraindicated in women who

are or may become pregnant.

    Mechanism of Action         
Methenolone is an anabolic steroid, which in high doses stimulates bone

marrow functions, particularly erythropoiesis.

CIMS Class : Anabolic Agents / Cytotoxic Chemotherapy

ATC Classification: A14AA04 – metenolone ; Belongs to

the class of androstan derivative anabolic steroids used

as systemic anabolic agents..

    Storage:

Store at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in

a tightly-closed container. Store away from heat, moisture, and light.

Do not store in the bathroom. Keep out of the reach of children

and away from pets.

Concentrex Laboratiories N. V., Moerstraat 58, 9031, Gent, Belgium

Reg. No. Licence: 253/55-C9/2010/BE
Manufactured under WHO cGMP guidelines
www.concentrexlabs.com
Date of Preparation : 19 july 2010